CSHL-led team discovers rare mutation dramatically increasing schizophrenia risk

CSHL-led team discovers rare mutation dramatically increasing schizophrenia risk: "The mutation identified in this study is a potent risk factor. 'In the general population this duplication is quite rare, occurring in roughly one in 5,000 persons', says Sebat, 'but for people that carry the extra copy, the risk of developing schizophrenia is increased by more than eight-fold'. This finding is the latest in a series of studies that have pinpointed rare CNVs that confer substantial risk of schizophrenia. Others include deletions on chromosomes 1, 15 and 22."